Dr. Fazal Wahab

 
PUBLICATIONS/RESEARCH WORK:
 

  • KISS1 and KISS1R DNA sequence variants in PCOS and GnRH deficiency patients.

 

  • Role of Kisspeptin-Kiss1r signaling in Metabolic regulation of Hypothalamic-Pituitary-Gonadal (HPG) axis in the adult male rhesus monkey.

 
Published peer-reviewed Research articles

  • Wahab F, Quinton R, Seminara SB. 2011. The kisspeptin signaling pathway and its role in human isolated GnRH deficiency. Molecular and Cellular Endocrinology; doi:10.1016/j.mce.2011.05.043
  • Wahab F, Ullah F, Chan YM, Seminara SB, Shahab M. 2011. Decrease in hypothalamic Kiss1 and Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta). Hormone and Metabolic Research 43(2): 81-85
  • Wahab F, Tanzeela R, Shahab M. 2011. Study of the effect of peripheral kisspeptin administration on basal and glucose-induced insulin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta). Hormone and Metabolic Research  43(1):37-42
  • Wahab F, Bano R, Jabeen S, Irfan S, Shahab M. 2010. Effect of peripheral kisspeptin administration on adiponectin, leptin, and resistin secretion under fed and fasting condition in the adult male rhesus monkey (Macaca mulatta). Hormone and Metabolic Research 42(8):570-74.
  • Wahab F, Aziz F, Irfan S, Zaman U, Shahab M. 2008. Short-term fasting attenuates the response of the HPG axis to kisspeptin challenge in the adult male rhesus monkey (Macaca mulatta). Life Sciences 83: 633-637.

 
 
Published Abstracts and Conference Presentations

  • Wahab F, Ullah F, Chan YM, Seminara SB, Shahab M. 2010. Decrease in hypothalamic Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta). International Congress of Neuroendocrinology (ICN2010), Rouen, France.
  • Mubeen H, Irfan S, Niaz A, Wahab F, Shahab M. 2010. Immunocytochemical detection of GPR54 receptor in the male rhesus monkey (Macaca mulatta) pituitary gland. International Congress of Neuroendocrinology (ICN2010), Rouen, France.
  • Wahab F 2010 Changes in GPR54 of PCOS patients, Gene team Meeting, Reproductive Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, USA.
  • Wahab F, Ullah F, Chan YM, Seminara SB, Shahab M. 2010. Quantification of hypothalamic Kiss1 and GnRH1 expression under fed and fasting in the adult male rhesus monkey (Macaca mulatta). 3rd National Symposium on Recent Advances in Endocrinology and Reproductive Sciences, University of Lahore, Lahore, Pakistan.
  • Wahab F, Tanzeela R, Shahab M. 2010. Study of the effect of peripheral kisspeptin administration on basal and glucose-induced insulin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta). BioVisionAxendria2010, Alexandria, Egypt.
  • Wahab F, Bano R, Jabeen S, Shahab M. 2009. Study of the effect of RFamide-related peptide-1 on the neuroendocrine reproductive axis in the adult male rhesus monkey (Macaca mulatta). 2nd School of Neuroendocrinology, Yufuin and Kitakyushu, Japan.
  • Wahab F, Bano R, Jabeen S, Shahab M. 2009. Novel role of kisspeptin in adipose tissue: stimulation of the adiponectin release. 36th International Congress of Physiological Science, Kyoto, Japan.
  • Wahab F, Shahab M. 2009. Kisspeptin as a link between metabolism and reproduction: evidences from rodent and primate studies. BioVision.NXT. Class of 2009, Lyon, France.
  • Bano R, Wahab F, Riaz T, Jabeen S, Irfan S, Arslan M, Shahab M.  2009. Peripheral metastin levels change in different pubertal stages in boys. Program of the 91st Annual Meeting of the Endocrine Society, Washington, USA.
  • Wahab F, Bano R, Riaz T, Shahab M. 2009 Primate HPG axis response to the peripheral kisspeptin challenge under the different time scales of fasting. 29th Pakistan Congress of Zoology, University of Sindh, Jamshooro, Pakistan.
  • Qaiser F, Wahab F, Wiqar MA, Hashim R, Leprince J, Vaudry H, Tena-Sempere M, Shahab M. Role of the evolutionary conserved 26 RF- and 43 RF- amides neuropeptides in the growth hormone release in the adult male rhesus monkey (Macaca mulatta). 29th Pakistan Congress of Zoology, University of Sindh, Jamshooro, Pakistan.
  • Wahab F, Irfan S, Zaman W, Shahab M. 2008. Differential response of primate HPG axis to kisspeptin and NMA challenge in hypoglycemic conditions. 1st world conference on kisspeptin signaling in the brain, Cordoba, Spain.
  • Wahab F, Salahuddin H, Anees M, Leprince J, Vaudry H, Tena-Sempere M, Shahab M. 2008. Study of the effect of 26 RF and 43 RF amides on neuroendocrine reproductive axis in adult male rhesus monkey (Macaca mulatta). 13th Congress of the European Neuroendocrine Association (ENEA), Antalya, Turkey.
  • Javaid A, Wahab F, Irfan S, Shahab M. 2008. Stimulatory effect of kisspeptin on oxytocin secretion in the adult male rhesus monkey (Macaca mulatta). 1st world conference on kisspeptin signaling in the brain, Cordoba, Spain.
  • Wahab F, Farzana Aziz, Muhammad Shahab. 2008. Peripheral kisspeptin challenge inhibits fasting and hypoglycemia stimulated cortisol secretion in the adult male rhesus monkey (Macaca mulatta). 1st South Asian Conference of Physiological Societies & 11th Biennial Conference of Pakistan Physiological Society, Islamabad, Pakistan.
  • Salahuddin H, Wahab F, Anees M, Leprince J, Vaudry H , Tena-Sempere M, Shahab M. 2008. Evidence that evolutionary conserved RF amide neuropeptides stimulate prolactin secretion in the adult male rhesus monkey (Macaca mulatta). 1st South Asian Conference of Physiological Societies & 11th Biennial Conference of Pakistan Physiological Society, Islamabad, Pakistan.
  • Wahab F, Bano R, Riaz T, Huma T, Irfan S, Shahab M. 2008. Study of the effect of peripheral kisspeptin administration on leptin secretion under fed and fasting condition in adult male rhesus monkey (Macaca mulatta). 1st South Asian Conference of Physiological Societies & 11th Biennial Conference of Pakistan Physiological Society, Islamabad, Pakistan.
  • Wahab F, Aziz F, Irfan S, Zaman U, Shahab M.  2008. HPG Axis Response to Kisspeptin Challenge Attenuates in Short-Term Fasting While Remains Preserved under Hypoglycemic Condition in the Adult Male Rhesus Monkey (Macaca mulatta). Program of the 90th Annual Meeting of the Endocrine Society, San Francisco, CA, USA, P1-677.
  • Irfan S, Anees M, Wahab F, Zaman U, Shahab M, Plant TM. 2008. Evidence for a Direct Intratesticular Action of Kisspeptin in the Adult Rhesus Monkey (Macaca mulatta). Program of the 90th Annual Meeting of the Endocrine Society, San Francisco, CA, USA, OR52-6.
  • Wahab F, Aziz F, Irfan S, Zaman U, Shahab M. 2007. Short-term fasting attenuates GnRH neuronal response to kisspeptin challenge in the adult male rhesus monkey (Macaca mulatta). International Symposium on “Recent trends in Endocrinology and Reproductive Sciences” Lahore, Punjab, Pakistan.

 
ANY OTHER INFORMATION:
 
Fellowships, awards, prizes and other distinctions                                                                                                                
 

  • Young Investigator Travel Grant (May 2010) granted by the International Neuroendocrine Federation (INF) for attending and presenting in the International Congress of Neuroendocrinology held in Rouen, France from 11-15th July 2010.
  • TWAS/BVA.NXT 2010 fellow selected by TWAS and BioVision Alexandria to attend BioVision.Alexandria from 10-15th April 2010 in Alexandria, Egypt.
  • International Research Support fellowship is provided by the Higher Education Commission of Pakistan for 6 months research work in the Endocrine Unit, Harvard Medical School, Harvard University, Boston, USA.
  • Young Investigator Travel Grant (February 2009) provided by the International Union of Physiological Sciences for presentation in the 36th Congress of Physiological Sciences to be held in Kyoto, Japan from 27th July to 1st August 2009.
  • Young Neuroendocrinologist Travel Award (August 2009) awarded by INF for participation in the 2nd School of Neuroendocrinology held in Yufuin and Kitakyushu, Japan.
  • BioVision.NXT.2009 Fellow (January 2009) selected by the World Life Sciences Forum from Asia on the basis of scientific achievements in the field of life science in 2008.
  • Biovision.NXT.2009 Fellow Travel Grant (March 2009) granted by World Life Sciences Forum to attend Biovision 2009 meeting held from 7-11 March 2009 in Lyon, France
  • ISI Journal Publication Allowance (2009) given by the Higher Education Commission (HEC) on publication in ISI journal.
  • Young Neuroendocrinologist Travel Award (October 2008) awarded by International Neuroendocrine Federation in Cordoba, Spain.
  • Ph.D. Student Travel Grant for paper presentation (October 2008) granted by HEC for oral presentation in the 1st World conference on Kisspeptin signaling in the Brain in Cordoba, Spain.
  • Dr. Atique Memorial Shield (November 2008) awarded by South Asian Association of Physiologists (SAAP) and Pakistan Physiological Society (PPS) for best presentation.
  • Indigenous Ph.D. fellowship (2006-2009) granted by HEC of Pakistan.
Designation: 
Assistant Professor
Area of Specialization: 
Endocrinology/ Reproductive Physiology
Qualification: 
Ph.D. (2011)
Faculty Picture: 
Department/Institute: